The interplay between oral microbes and immune responses

Oral microbes play a critical role in maintaining oral homeostasis. Microbial dysbiosis promotes disease pathogenesis through several mechanisms. Recent studies have revealed that microbial imbalance and sustained inflammation are involved progression. The adverse interaction triggered by host immune response to microorganisms can lead systemic diseases. Here, we reviewed how communicate with hosts during the development of local distant inflammation. Elucidation these processes may reveal future directions this field potential targets novel biological therapies for